Founder of Mirsinidi Monastery is the monk Christoforos Seremelis (1897). It is dedicated to Panagia Myrtidiotissa (Virgin of the Myrtles) of the miraculous icon which the monk found in the sea below the monastery. It celebrates its feast day on September 24 when crowds of worshippers come to honor Her Grace.

The monastery offered valuable philanthropic services during the German occupation as well as during the resistance movement of World War II.

The vestments of the national martyr Gregory V are kept here. The monastery, which house four monks, includes guest quarters.